Our Recommended Replacement

Use Coupon Code labz1010 to save 10% today!

  • Chemyo Description

  • Sarmlabz Description

  • reviews

MK677 | MK-677 Ibutamoren Solution 25mg/ml – 50ml

MK-677 2.5% solution. High affinity ghrelin receptor agonist (pKi = 8.14). Growth hormone (GH) secretagog; stimulates GH release from rat pituitary cells in vitro (EC50 = 1.3 nM) and enhances GH plasma levels in vivo.

ApplicationA potent, non-peptide ghrelin receptor agonist
Concentration2,5% (25mg/ml)
Composition10% ethanol, 87.5% deionized water, 2.5% MK-677 (>98% purity)
CAS159752-10-0
Molar Mass528.662 g/mol
Chemical FormulaC27H36N4O5S
SynonymsIbutamoren, MK-677, MK-0677, L-163,191, L163191, Nutrobal
StorageMinimize open air exposure, store in a cool dry place
Third-party tested for identitypurity, and concentration
  • 50ml bottles | almost 70% more volume compared to 30ml
  • Induction sealed and batch coded
  • Free shipping US $100+ | international $275+
  • A secretagogue is a compound that stimulates the secretion of another substance. MK-677, or Ibutamoren, belongs to this class of compounds, as it stimulates the secretion of growth hormone. Oftentimes it is mistakenly considered as a SARM. This erroneous classification comes from the fact that this compound acts in a very similar way to the naturally occurring hormone, ghrelin, by triggering an increase of GH in human subjects. This substance is able to boost the amounts of IGF-I. As opposed to many other similar substances, MK-677 doesn't need to be injected to be absorbed by the body, as it is 100% orally absorbable. If you were currently looking to buy MK-677 online, you've come to the right place, so feel free to place your order right now!

     Here are the most important effects of taking MK-677:

    •  Higher growth hormone amounts in the body
    • Higher bone density
    • Muscle mass building
    • More rapid muscle building
    • Stronger immunity
    • Improved appetite
    • Better quality of sleep
    • GH deficit reversal

    Information 

    Nevertheless, we have to warn you that Ibutamoren has no FDA approval for human use so far. It can be used only as part of scientific studies.

     On the bright side of things, research has shown that MK-677 could have a huge potential to boost your health in so many ways!

     The results of one of these studies revealed increases of the IGF-I, respectively IGFBP-3 amounts in subjects who took MK-677. This means it has the potential to reverse somatotropic deficits. (G Copinschi, A Van Onderbergen, M L’Hermite-Balériaux, C M Mendel, A Caufriez, R Leproult, J A Bolognese, M De Smet, M O Thorner, E Van Cauter, Effects of a 7-day treatment with a novel, orally active, growth hormone (GH) secretagogue, MK-677, on 24-hour GH profiles, insulin-like growth factor I, and adrenocortical function in normal young men, The Journal of Clinical Endocrinology & Metabolism, Volume 81, Issue 8, 1 August 1996, Pages 2776–2782, https://academic.oup.com/jcem/article/81/8/2776/2875610)

     More research work focused on the effects of MK-677 on the bones. Its results are also promising, as it appears that this compound can increase osteoblast activity and bone renewal in elderly individuals. (Murphy MG, Bach MA, Plotkin D, Bolognese J, Ng J, Krupa D, et al. Oral administration of the growth hormone secretagogue MK-677 increases markers of bone turnover in healthy and functionally impaired elderly adults. The MK-677 Study Group. J Bone Miner Res. 1999;14:1182–1188.)

     More research results are yet to be released over the next few years.

     When you order, therefore, keep in mind that this product is aimed solely for lab research purposes, as it doesn't have the FDA approval for humans. To put it in simple words, this product is not a food supplement, so you shouldn't use it as such.

    M-677 FAQ's

    Where Do I Buy MK-677 Nutrobal?

    - We offer the best sources for this product. If you didn't find it in the quantities you would like then, please contact us.
    While you can find Ibutamoren for sale in many places, our shop stands out of the crowd due to the high quality of our products and the seamless customer support. With us, you can rest assured that you'll get Ibutamoren of minimum 98% purity (with certification).We provide next day shipping in most places. Just contact us for any questions you may have.

    Can NK-677 increase growth hormone levels and IGF-I in a similar manner to the human growth hormone treatment?

    According to research, MK-677 is capable to boost bodily amounts of HGH and IGF-I.

    Is there a danger that MK677 might compromise the body's naturally occurring growth hormone production?

    For the time being, there's no evidence that MK677 can suppress natural GH production in the human body. As more research gets done, the information will be updated.

    Does MK677 suppress natural testosterone production?

    The mechanism of action of MK677 has no connection to the testosterone feedback loop, so it shouldn't affect naturally occurring testosterone in any way.


    References:

    1. https://academic.oup.com/jcem/article/81/8/2776/2875610
    2. https://pubmed.ncbi.nlm.nih.gov/10404019/


    Related Products